The Red Herring editorial team selected the 2010 winners as the most innovative companies from a pool of hundreds from across Europe. The Top 100 Europe are evaluated on both quantitative and qualitative criteria, such as financial performance, technology innovation, quality of management, execution of strategy, and integration into their respective industries.
| Accumulate AB | Sweden |
| ALWIL Software a.s. | Czech Republic |
| Apsmart Ltd | United Kingdom |
| attracTV | Israel |
| Bioprocess Control AB | Sweden |
| Bizk.it | United Kingdom |
| BlueTeach | France |
| BMEYE | The Netherlands |
| Bookioo World | Spain |
| BoosterMedia | The Netherlands |
| BriefCam Ltd. | Israel |
| Busuu.com | Spain |
| Cellictica Ltd. | Finland |
| Clean Mobile AG | Germany |
| CommProve Ltd. | United Kingdom |
| Copernica BV | The Netherlands |
| Datanomic | United Kingdom |
| deal united GmbH | Germany |
| Digium Ltd | Finland |
| Eniram Ltd | Finland |
| EnQii Group | United Kingdom |
| Excentive | France |
| EXCICO group NV | Belgium |
| Flimmit GmbH | Austria |
| Flogs International | The Netherlands |
| Flowdock Ltd | Finland |
| fonYou Telecom | Spain |
| GetJar Inc. | Lithuania |
| GigsWiz.com Ltd | Finland |
| GoAdv | United Kingdom |
| Helveta Ltd | United Kingdom |
| HulloMail Ltd | United Kingdom |
| Hypios | France |
| Ideakone Ltd | Finland |
| Intelen | Greece |
| Ipanema Technologies | France |
| Iptego | Germany |
| ITS | United Kingdom |
| Kobalt Music Group | United Kingdom |
| Lagan Technologies | United Kingdom |
| LeadMedia | France |
| Load Impact | Sweden |
| Maeglin Software SA | France |
| Mayoris AG | Switzerland |
| meebee.com | Czech Republic |
| memonic.com | Switzerland |
| Mister Spex GmbH | Germany |
| mixd.tv | Germany |
| Mobiento | Sweden |
| Movidius | Ireland |
| MS Tech Ltd. | Israel |
| Music Networx | Germany |
| Natural User Interface Technologies | Sweden |
| Nomadesk | Belgium |
| Octoshape Aps | Denmark |
| Ogone SA/NV | Belgium |
| Pancomp International Ltd | Finland |
| PassivSystems | United Kingdom |
| Popmog | Germany |
| Qosmos | France |
| QuestBack AS | Norway |
| Quisma GmbH | Germany |
| Racktivity | Belgium |
| Red Solution Finland Oy | Finland |
| ReformTech Sweden AB | Sweden |
| Retailo AG | Germany |
| RunMyProcess | France |
| SalsaDev | Switzerland |
| Santaris Pharma A/S | Denmark |
| Secunia ApS | Denmark |
| Sentry Wireless | Ireland |
| Shazam | United Kingdom |
| Sibesonke Oy | Finland |
| Silentale | France |
| SmartGrains | France |
| Snoobi Oy | Finland |
| SolarEdge Technologies Ltd. | Israel |
| Spartoo SAS | France |
| Sports Alliance Limited | United Kingdom |
| Squace Mobile AB | Sweden |
| Statista GmbH | Germany |
| SundaySky | Israel |
| TaKaDu | Israel |
| Talend | France |
| Tobii Technology | Sweden |
| Torqeedo | Germany |
| Transmode Systems | Sweden |
| Trusteer | Israel |
| TV Genius | United Kingdom |
| Upstream Systems | Greece |
| Vidamo AS | Norway |
| Vipventa, SL | Spain |
| Virtensys | United Kingdom |
| Vringo | United Kingdom |
| Waze | Israel |
| wunderloop media services | Luxemburg |
| WWG worldwidegames | Germany |
| Xelerated AB | Sweden |
| Zeus Technology | United Kingdom |
| Zonerider Networks | United Kingdom |
| Zoomio | Denmark |